COVID vaccine efficacy against severe illness just under 50% in 2003 --European studies

COVID vaccine efficacy against severe illness just under 50%, per early estimates from 2023 Two European observational studies estimate the vaccine effectiveness (VE) of the COVID-19 XBB.1.5 vaccine approved in fall 2023 against hospitalization, the first one finding 49% overall VE in adults, and one showing good protection—but uneven uptake—among pregnant women. CIDRAP

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"The findings of our study suggest that the adapted COVID-19 XBB.1.5 vaccines provided protection against hospitalisation in the first 3.5 months post vaccination, by reducing the risk of COVID-19 hospitalisation by approximately half among the vaccinated individuals," they concluded.

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