U.S. Overview: USA TODAY 80% of Americans 12 and over have first dose; Michigan is nation's hot spot as infections rise in 33 states.

-- The U.S. reached an encouraging milestone Wednesday with 80% of Americans ages 12 and older having received at least one dose of a coronavirus vaccine, President Joe Biden's coronavirus response coordinator said. ...

-- For much of the pandemic, some Americans fearful of contracting COVID-19 have steered clear of elevators and opted for the stairs. A recent report suggests elevators likely aren't a high source of coronavirus transmission.

Purdue University researchers simulated airborne particle exposure for people riding a typical elevator with a person who is infected with COVID-19, according to the study published last week in the peer-reviewed journal Building and Environment and commissioned by Otis Elevator. ...

-- Michigan catapulted Tuesday to the worst COVID-19 hot spot in the nation, as the seven-day case rate rose to 503.8 per 100,000 residents, according to the CDC. Cases are rising in 33 states, a USA TODAY analysis of Johns Hopkins University data shows. Cases for the week ending Monday were at 584,449, up 15% from a recent low in the week ending Oct. 26. ...

--The pandemic has spurred many workers to reevaluate their lives and the role work plays in them, leading some to set fresh boundaries, find new jobs or maintain the side gigs that got them through the shutdowns and layoffs. Nearly six in 10 American workers in an October survey by job search site LinkedIn said they had gone through a career awakening during the COVID-19 pandemic, whether it was a desire for better work-life balance, deciding to pursue a promotion or redefining their meaning of success.